How to read this page
An ingredient list is product information. It tells you what a manufacturer says is present. It is not evidence of efficacy, and it becomes considerably less informative when amounts are withheld — because in nutrition the amount is usually the whole question. Every entry below therefore separates three things: the stated role, the research context, and the practical considerations.
Where information is unavailable we write “not clearly disclosed in the product information reviewed” rather than filling the gap with a plausible-looking number. Inventing a dosage to make a table look complete is the most common failure in supplement reviews and we will not do it.
Prostadine ingredients table
| Ingredient | Why it is included | Evidence context | Important considerations |
|---|---|---|---|
| Nori Yaki Extract Powder Limited | Listed in the product materials as a marine (red algae) ingredient included for general prostate and urinary support. | Nori (Porphyra species) is a well-studied food seaweed with documented nutrient content, including iodine, protein and polysaccharides. Published research is mostly nutritional and laboratory work; we found no clinical trial testing nori extract as a treatment for prostate or urinary symptoms. | Seaweeds vary widely in iodine content. People with thyroid conditions or seafood/algae sensitivities should speak with a clinician before using seaweed-based supplements. |
| Wakame Extract Preliminary | Listed as a marine brown-algae ingredient described in product materials as supporting healthy urinary function. | Wakame (Undaria pinnatifida) contains fucoidan and fucoxanthin, both of which have been examined in laboratory and animal studies. Human evidence relevant to prostate or urinary outcomes is not established. | Another iodine-containing seaweed. Cumulative iodine intake matters when several algae appear in one formula. |
| Kelp Powder Limited | Listed as a marine ingredient; product materials associate it with antioxidant content. | Kelp is a recognised dietary source of iodine and minerals. Antioxidant activity is documented in laboratory settings. Clinical outcomes for prostate health have not been demonstrated in trials of kelp itself. | Kelp is one of the most iodine-dense foods and can also concentrate heavy metals depending on harvest source. Sourcing and testing information is not detailed in the product materials we reviewed. |
| Bladderwrack Powder Preliminary | Listed as a seaweed ingredient described in marketing as supporting bladder and prostate cell health. | Bladderwrack (Fucus vesiculosus) has traditional use and laboratory data on fucoidans and phlorotannins. Human trials relevant to benign prostate symptoms were not identified. | Documented interactions with thyroid function and with anticoagulant medicines have been reported for bladderwrack in the literature. |
| Saw Palmetto Mixed | The most familiar prostate-associated ingredient in the formula; described in product materials as supporting normal urinary flow. | Saw palmetto (Serenoa repens) is the best-researched ingredient here. Randomised trials and Cochrane reviews of standardised saw palmetto extracts for lower urinary tract symptoms of benign prostatic hyperplasia have produced mixed results, with larger, better-controlled trials such as the NIH-funded STEP and CAMUS studies finding no meaningful benefit over placebo at the doses tested. | Generally well tolerated in trials; mild gastrointestinal effects were the most commonly reported. Results also depend heavily on extract type and dose, neither of which is quantified in the Prostadine materials we reviewed. |
| Pomegranate Extract Mixed | Listed for antioxidant content and, in marketing copy, for circulation. | Pomegranate polyphenols have been studied in small human trials, including work on PSA doubling time in men treated for prostate cancer. Findings have been inconsistent and later randomised placebo-controlled work did not confirm early positive signals. | Pomegranate has been reported to affect some drug-metabolising enzymes; relevant if you take prescription medication. |
| Iodine Moderate | Listed as a discrete ingredient in addition to the four seaweed sources. | Iodine is an essential nutrient with an established role in thyroid hormone production. The NIH Office of Dietary Supplements sets an adult RDA of 150 mcg and a tolerable upper intake level of 1,100 mcg per day. Iodine is not an established treatment for prostate conditions. | This is the single most important safety item in the formula. Excess iodine can cause both hypothyroidism and hyperthyroidism in susceptible people. The amount of iodine per serving is not clearly disclosed in the product information we reviewed. |
| Shilajit Preliminary | Listed as a mineral-rich resin, described in marketing as supporting energy and vitality. | Small human studies have examined purified shilajit for fatigue and for male reproductive parameters. Sample sizes are small and independent replication is limited. | Quality varies. Unpurified shilajit has been reported to contain heavy metals, so processing and testing matter; the product materials do not describe purification standards. |
| Neem Preliminary | Listed as a botanical, described in marketing in general 'cleansing' terms. | Neem (Azadirachta indica) has extensive laboratory literature on antimicrobial and anti-inflammatory activity. Human trial evidence for urinary or prostate outcomes was not identified. | Neem oil in particular has documented toxicity concerns at high intakes and is generally not advised alongside fertility treatment. The form and quantity used in Prostadine is not disclosed. |
What the label does not disclose
- Quantities. No milligram amounts per ingredient were published in the materials we reviewed.
- Extract standardisation. Saw palmetto trials use specific lipidosterolic extracts standardised to a fatty acid content. Whether the saw palmetto here matches any studied extract is unknown.
- Iodine content per serving. Given four seaweeds plus discrete iodine, this is the number most worth publishing and it is the one we could not find.
- Heavy metal and contaminant testing. Seaweeds and unpurified shilajit can concentrate heavy metals. We found no published certificates of analysis.
- Manufacturer and facility identity. Not clearly named.
Evidence map
The table below maps each ingredient to the type of research available and how relevant it is to the finished product. Note how the last column reads: in every row, relevance to Prostadine specifically is limited by unknown dosing.
| Ingredient | Human research exists? | Type of evidence | Relevance to finished product |
|---|---|---|---|
| Saw Palmetto | Yes, substantial | Randomised controlled trials, Cochrane reviews (mixed to negative for LUTS) | Limited — dose and extract type undisclosed |
| Pomegranate Extract | Yes, limited | Small trials in prostate cancer populations; later RCT unconfirmed | Low — different population and outcome |
| Iodine | Yes, extensive | Established nutrient science (thyroid function) | Safety-relevant rather than efficacy-relevant |
| Shilajit | Yes, small | Small trials on fatigue and reproductive markers | Low — not a prostate or urinary outcome |
| Kelp / Nori / Wakame / Bladderwrack | Not for this use | Nutritional composition, laboratory and animal studies of isolated compounds | Low — mechanism-level only |
| Neem | Not for this use | Laboratory antimicrobial and anti-inflammatory work | Low — no human urinary outcome data identified |
Affiliate link to the official offer, where the current label and directions are shown. Formulas change — always read the bottle you receive.
Ingredient by ingredient
Nori Yaki Extract Powder
Product information. Listed in the product materials as a marine (red algae) ingredient included for general prostate and urinary support.
Research context. Nori (Porphyra species) is a well-studied food seaweed with documented nutrient content, including iodine, protein and polysaccharides. Published research is mostly nutritional and laboratory work; we found no clinical trial testing nori extract as a treatment for prostate or urinary symptoms.
Considerations. Seaweeds vary widely in iodine content. People with thyroid conditions or seafood/algae sensitivities should speak with a clinician before using seaweed-based supplements.
Quantity per serving: not clearly disclosed in the product information reviewed.
Wakame Extract
Product information. Listed as a marine brown-algae ingredient described in product materials as supporting healthy urinary function.
Research context. Wakame (Undaria pinnatifida) contains fucoidan and fucoxanthin, both of which have been examined in laboratory and animal studies. Human evidence relevant to prostate or urinary outcomes is not established.
Considerations. Another iodine-containing seaweed. Cumulative iodine intake matters when several algae appear in one formula.
Quantity per serving: not clearly disclosed in the product information reviewed.
Kelp Powder
Product information. Listed as a marine ingredient; product materials associate it with antioxidant content.
Research context. Kelp is a recognised dietary source of iodine and minerals. Antioxidant activity is documented in laboratory settings. Clinical outcomes for prostate health have not been demonstrated in trials of kelp itself.
Considerations. Kelp is one of the most iodine-dense foods and can also concentrate heavy metals depending on harvest source. Sourcing and testing information is not detailed in the product materials we reviewed.
Quantity per serving: not clearly disclosed in the product information reviewed.
Bladderwrack Powder
Product information. Listed as a seaweed ingredient described in marketing as supporting bladder and prostate cell health.
Research context. Bladderwrack (Fucus vesiculosus) has traditional use and laboratory data on fucoidans and phlorotannins. Human trials relevant to benign prostate symptoms were not identified.
Considerations. Documented interactions with thyroid function and with anticoagulant medicines have been reported for bladderwrack in the literature.
Quantity per serving: not clearly disclosed in the product information reviewed.
Saw Palmetto
Product information. The most familiar prostate-associated ingredient in the formula; described in product materials as supporting normal urinary flow.
Research context. Saw palmetto (Serenoa repens) is the best-researched ingredient here. Randomised trials and Cochrane reviews of standardised saw palmetto extracts for lower urinary tract symptoms of benign prostatic hyperplasia have produced mixed results, with larger, better-controlled trials such as the NIH-funded STEP and CAMUS studies finding no meaningful benefit over placebo at the doses tested.
Considerations. Generally well tolerated in trials; mild gastrointestinal effects were the most commonly reported. Results also depend heavily on extract type and dose, neither of which is quantified in the Prostadine materials we reviewed.
Quantity per serving: not clearly disclosed in the product information reviewed.
Pomegranate Extract
Product information. Listed for antioxidant content and, in marketing copy, for circulation.
Research context. Pomegranate polyphenols have been studied in small human trials, including work on PSA doubling time in men treated for prostate cancer. Findings have been inconsistent and later randomised placebo-controlled work did not confirm early positive signals.
Considerations. Pomegranate has been reported to affect some drug-metabolising enzymes; relevant if you take prescription medication.
Quantity per serving: not clearly disclosed in the product information reviewed.
Iodine
Product information. Listed as a discrete ingredient in addition to the four seaweed sources.
Research context. Iodine is an essential nutrient with an established role in thyroid hormone production. The NIH Office of Dietary Supplements sets an adult RDA of 150 mcg and a tolerable upper intake level of 1,100 mcg per day. Iodine is not an established treatment for prostate conditions.
Considerations. This is the single most important safety item in the formula. Excess iodine can cause both hypothyroidism and hyperthyroidism in susceptible people. The amount of iodine per serving is not clearly disclosed in the product information we reviewed.
Quantity per serving: not clearly disclosed in the product information reviewed.
Shilajit
Product information. Listed as a mineral-rich resin, described in marketing as supporting energy and vitality.
Research context. Small human studies have examined purified shilajit for fatigue and for male reproductive parameters. Sample sizes are small and independent replication is limited.
Considerations. Quality varies. Unpurified shilajit has been reported to contain heavy metals, so processing and testing matter; the product materials do not describe purification standards.
Quantity per serving: not clearly disclosed in the product information reviewed.
Neem
Product information. Listed as a botanical, described in marketing in general 'cleansing' terms.
Research context. Neem (Azadirachta indica) has extensive laboratory literature on antimicrobial and anti-inflammatory activity. Human trial evidence for urinary or prostate outcomes was not identified.
Considerations. Neem oil in particular has documented toxicity concerns at high intakes and is generally not advised alongside fertility treatment. The form and quantity used in Prostadine is not disclosed.
Quantity per serving: not clearly disclosed in the product information reviewed.
Is the ingredient list the same as older versions?
Direct-response supplement formulas are revised, and older reviews circulating online describe earlier versions. The nine ingredients above reflect the product information available at the time of this update. If you are comparing against an older article and the lists differ, trust the current official label over any review page, including this one.
Sources consulted
- NIH Office of Dietary Supplements — Iodine fact sheet
- NCCIH — Saw palmetto
- Barry M.J. et al., CAMUS randomised trial of saw palmetto extract, JAMA 2011
- Paller C.J. et al., randomised placebo-controlled trial of pomegranate extract and PSA doubling time
- FDA — Dietary supplement labelling and Supplement Facts requirements
- Current publicly available Prostadine product information page, reviewed September 2026
Product details are recorded as they appeared in the materials we reviewed. Formulas, directions, pricing and guarantee terms can change without notice; always confirm on the current official product page.